The scheme, which will redevelop the area around Old Jamaica Road and St James's Church, will include 400 homes, 100 live–work units, shops and health centres.
Kennedy Haywards, an architect, services engineer and surveyor, said the designs for the scheme would include a sustainability strategy including grass roofs, a car-sharing scheme and on-site water recycling.
The practice said it was also planning a 10-storey photovoltaic screen for a 15-storey tower planned for the site.
Kennedy Haywards project director Julian Hampson said the project was a significant one. He said: "It's one of the last few big central London sites. We are very excited about it."
Hampson said the firm was in talks with contractors to build the scheme, which is due to go on site next year and take three years to construct.
Kennedy Haywards, formed in April last year, is a merger of architect Chiltern Cunningham Associates, Haywards Chartered Surveyors and services engineer Mackechnie Jarvis & Graham.