The scheme will involve demolition of the Ferrier estate and the construction of public buildings close to an area where teenager Stephen Lawrence was murdered on 22 April 1993.
The cost of delivering the entire masterplan is set to exceed £550m.
Building understands that developers Countryside Properties, Crest Nicholson and Bellway Homes intend to bid. Registered social landlords Hyde, Southern Housing Group, Moat Housing Group, and London & Quadrant Group are lining up bids with developers.
It is understood that HTA Architects and Watkins Gray International are also considering bids.
The consultation process has been the most extensive we’ve ever done in the borough
Greenwich council spokesperson
The plan is for 4400 homes, transport links with Kidbrooke Station, two schools, a library and other community facilities.
An initial masterplan by planner EDAW and HTA Architects was delivered in April 2002.
Since then, Greenwich council has been working with regeneration agency English Partnerships over proposals to share some of the risks and costs associated with such a large scheme.